Abstract

Garrè’s osteomyelitis is a rare inflammatory disease with an unclear aetiology. It mainly affects the mandible in young children and adults under 30 years old. The goal of the treatment is to control the symptoms. However, the most appropriate management remains unclear. There are reports of off-label use of antiresorptive drugs, namely bisphosphonates, in patients with refractory disease, with favourable outcomes. 

In this article we present a literature review about Garrè’s osteomyelitis and a case report of a patient with this diagnosis, refractory to conventional treatments and symptomatic over the previous five years, who was effectively treated with zoledronic acid.

Keywords

• Osteomyelitis
• Mandible
• Periostitis
• Bisphosphonates
• Zoledronic Acid

References

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